Actively Acquired Tolerance to Dinitrochlorobenzene. Tests in Newborn Guinea Pigs
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چکیده
منابع مشابه
Hypersensitivity in Newborn Guinea Pigs
Neonatal guinea pigs during the first 2 weeks of life did not indicate the presence of delayed hypersensitivity intradermally, after sensitization with purified soluble antigens in dose levels that induced detectable delayed hypersensitivity in the skin of adults. Although Arthus type allergy was detectable in newborns, circulating antibody frequently preceded its appearance by several days. Pa...
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One- to three-day-old guinea pigs were inoculated intranasally with the chlamydial agent of guinea pig inclusion conjunctivitis. Physical signs of infection included a marked increase in respiration rate on days 5 to 10 of infection and radiographic evidence of pneumonia on day 6. When animals were killed at various times after infection and lung tissue was examined by histopathology, evidence ...
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The phenomenon of “actively acquired toler ance― to foreign cells was demonstrated experi mentally by Billingham, Brent, and Medawar (1) in 1953. They observed that, if animals were given injections, during embryonic life, of cells from a foreign strain, they would accept, during subse quent adult life, skin grafts from the same foreign strain which would normally be incompatible. The effec...
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Billingham et al.' reported that mice and chickens injected as embryos with cells from other strains acquired a persistent tolerance to later skin grafts from the donor strains. It seemed possible to us that a similar, but naturally acquired, tolerance might be in part responsible for the variation in response of Rh-negative persons exposed to the Rh antigens.2 The hypothesis to be tested was t...
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National Library of Medicine, Cataloging in Publication Contact allergy predictive tests m guinea pigs Volume editors, K.E. Andersen, H I.Maibach. Basel, New York Karger, 1985 -(Current problems in dermatology, vol. 14) Includes bibliographies and index. 1 Dermatitis, Contact etiology 2. Guinea Pigs 3 Skin Tests I Andersen, K E. (Klaus E.) II. Maibach, Howard I III Series W1 CU804L v 14 [WR 175...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1963
ISSN: 0022-202X
DOI: 10.1038/jid.1963.121